The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica
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| Formato: | Online |
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Universidad Nacional, Costa Rica
2019
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| Acceso en línea: | https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13267 |
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VETERINARIA132672021-11-26T05:13:34Z The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica El caballo como modelo para la investigación ortopédica traslacional: Ejemplos de estudios sobre la regeneración de cartílago y hueso conducidos en Costa Rica Vindas Bolaños, Rafael Malda, Jos van Weeren, René de Grauw, Janny The paper provides results published or to be published of long-term in vivo equine studies to evaluate techniques of possible regenerative matrices of cartilage and bone, by means of cell-free implants or stimulation of the bone marrow. From the fixation techniques analyzed, it can be concluded that the best alternatives are the pressure technique for subchondral defects and a novel hydrogel with self-adhesive capacity for chondral defects. The equine coxal tuberosity was used for the first time as a model for regeneration studies of bone defects, analyzing scaffolds based on tricalcium phosphate, polymers and nanoparticles, by means of 3-D printing. Osteoconductivity, osteoinductivity, and the importance of microporosity were documented.Given that decellularized materials do not always give significant desired results in the regeneration of cartilage, it is important to conduct long-term studies. The technique of nanofracture and a novel self-adhesive hydrogel in the knee of the equine showed promising preliminary results in the regeneration of cartilage.The knee and the coxal tuberosity of the horse represent models of studying cartilage and bone regeneration in a true translational sense as a source of highly valuable information for clinical studies, for both horses and humans. Universidad Nacional, Costa Rica 2019-12-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion texto Documentos application/pdf text/html application/epub+zip https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13267 10.15359/rcv.37-3.2 Ciencias Veterinarias; Vol 37 No 3 (2019): Suplement: First Symposium on Regenerative Medicine and Nanotechnology; 9-10 Ciencias Veterinarias; Vol. 37 Núm. 3 (2019): Suplemento: Simposio de Medicina Regenerativa y Nanotecnología; 9-10 2215-4507 0250-5649 eng https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13267/18594 https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13267/18673 https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13267/18686 Copyright (c) 2019 Revista Ciencias Veterinarias https://creativecommons.org/licenses/by-nc-nd/3.0/cr/ |
| institution |
Universidad Nacional de Costa Rica |
| collection |
Ciencias Veterinarias |
| language |
eng |
| format |
Online |
| author |
Vindas Bolaños, Rafael Malda, Jos van Weeren, René de Grauw, Janny |
| spellingShingle |
Vindas Bolaños, Rafael Malda, Jos van Weeren, René de Grauw, Janny The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica |
| author_facet |
Vindas Bolaños, Rafael Malda, Jos van Weeren, René de Grauw, Janny |
| author_sort |
Vindas Bolaños, Rafael |
| title |
The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica |
| title_short |
The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica |
| title_full |
The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica |
| title_fullStr |
The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica |
| title_full_unstemmed |
The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica |
| title_sort |
horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in costa rica |
| title_alt |
El caballo como modelo para la investigación ortopédica traslacional: Ejemplos de estudios sobre la regeneración de cartílago y hueso conducidos en Costa Rica |
| publisher |
Universidad Nacional, Costa Rica |
| publishDate |
2019 |
| url |
https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13267 |
| work_keys_str_mv |
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