3D polymeric scaffolds for oral tissue regeneration
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Universidad Nacional, Costa Rica
2019
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Acceso en línea: | https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284 |
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VETERINARIA132842021-11-26T05:13:34Z 3D polymeric scaffolds for oral tissue regeneration Andamios poliméricos 3D para regeneración de tejido oral Chavarría-Bolaños, Daniel Villalobos, Diana Vega-Baudrit, José Roberto A fundamental base of bioengineering and tissue regeneration is the selection and development of the scaffolds responsible for cell growth. However, finding the “ideal” scaffold depends not only on proposing an innovative idea, but also on considering multiple chemical, biological, and physical aspects that can be manipulated to optimize their future clinical performance. Multiple local variables (such as local inflammation, vascularity, tissue damage, immune response, among others), as well as systemic variables (diseases or concomitant treatments) can favor or affect the scaffold behavior in each case. The selection of the ideal scaffold for each case involves three indispensable steps: design, selection of manufacturing material, and visualization of the future biological function that each biomaterial will perform. The design is always a parallel process with the selection of the ideal biomaterial. Certain “light” scaffolds (such as membranes, hydrogels, or sponges) will require the use of polymers that allow their simple manipulation and early degradation, which in turn can favor the release of charged molecules previously included, obtaining an active scaffold known as drug delivery system. On the other hand, structural scaffolds that are prone to replace block compromised structures may need different designs and production techniques, where three-dimensional printing is included. All of these options should consider important aspects such as bioactivity, regenerative capacity, and biological response of the surrounding tissues. Some alternatives may induce greater cell adhesion and proliferation, while optimizing the osseointegration and healing processes. Other alternatives may play a more “active” role while promoting regeneration processes and controlling local infectious diseases or painful responses. In order to look for the best translational approach of the biomaterial, each option must be chosen with the correct diagnosis of the case to be treated. Universidad Nacional, Costa Rica 2019-12-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion text Documentos application/pdf text/html application/epub+zip https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284 10.15359/rcv.37-3.10 Ciencias Veterinarias; Vol. 37 No. 3 (2019): Suplement: First Symposium on Regenerative Medicine and Nanotechnology; 28 Ciencias Veterinarias; Vol. 37 Núm. 3 (2019): Suplemento: Simposio de Medicina Regenerativa y Nanotecnología; 28 2215-4507 0250-5649 eng https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284/18622 https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284/18681 https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284/18694 Copyright (c) 2019 Revista Ciencias Veterinarias |
institution |
Universidad Nacional de Costa Rica |
collection |
Ciencias Veterinarias |
language |
eng |
format |
Online |
author |
Chavarría-Bolaños, Daniel Villalobos, Diana Vega-Baudrit, José Roberto |
spellingShingle |
Chavarría-Bolaños, Daniel Villalobos, Diana Vega-Baudrit, José Roberto 3D polymeric scaffolds for oral tissue regeneration |
author_facet |
Chavarría-Bolaños, Daniel Villalobos, Diana Vega-Baudrit, José Roberto |
author_sort |
Chavarría-Bolaños, Daniel |
title |
3D polymeric scaffolds for oral tissue regeneration |
title_short |
3D polymeric scaffolds for oral tissue regeneration |
title_full |
3D polymeric scaffolds for oral tissue regeneration |
title_fullStr |
3D polymeric scaffolds for oral tissue regeneration |
title_full_unstemmed |
3D polymeric scaffolds for oral tissue regeneration |
title_sort |
3d polymeric scaffolds for oral tissue regeneration |
title_alt |
Andamios poliméricos 3D para regeneración de tejido oral |
publisher |
Universidad Nacional, Costa Rica |
publishDate |
2019 |
url |
https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284 |
work_keys_str_mv |
AT chavarriabolanosdaniel 3dpolymericscaffoldsfororaltissueregeneration AT villalobosdiana 3dpolymericscaffoldsfororaltissueregeneration AT vegabaudritjoseroberto 3dpolymericscaffoldsfororaltissueregeneration AT chavarriabolanosdaniel andamiospolimericos3dpararegeneraciondetejidooral AT villalobosdiana andamiospolimericos3dpararegeneraciondetejidooral AT vegabaudritjoseroberto andamiospolimericos3dpararegeneraciondetejidooral |
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1805400499689619456 |