3D polymeric scaffolds for oral tissue regeneration

Detalles Bibliográficos
Autores principales: Chavarría-Bolaños, Daniel, Villalobos, Diana, Vega-Baudrit, José Roberto
Formato: Online
Idioma:eng
Publicado: Universidad Nacional, Costa Rica 2019
Acceso en línea:https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284
id VETERINARIA13284
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spelling VETERINARIA132842021-11-26T05:13:34Z 3D polymeric scaffolds for oral tissue regeneration Andamios poliméricos 3D para regeneración de tejido oral Chavarría-Bolaños, Daniel Villalobos, Diana Vega-Baudrit, José Roberto A fundamental base of bioengineering and tissue regeneration is the selection and development of the scaffolds responsible for cell growth. However, finding the “ideal” scaffold depends not only on proposing an innovative idea, but also on considering multiple chemical, biological, and physical aspects that can be manipulated to optimize their future clinical performance. Multiple local variables (such as local inflammation, vascularity, tissue damage, immune response, among others), as well as systemic variables (diseases or concomitant treatments) can favor or affect the scaffold behavior in each case. The selection of the ideal scaffold for each case involves three indispensable steps: design, selection of manufacturing material, and visualization of the future biological function that each biomaterial will perform. The design is always a parallel process with the selection of the ideal biomaterial. Certain “light” scaffolds (such as membranes, hydrogels, or sponges) will require the use of polymers that allow their simple manipulation and early degradation, which in turn can favor the release of charged molecules previously included, obtaining an active scaffold known as drug delivery system. On the other hand, structural scaffolds that are prone to replace block compromised structures may need different designs and production techniques, where three-dimensional printing is included. All of these options should consider important aspects such as bioactivity, regenerative capacity, and biological response of the surrounding tissues. Some alternatives may induce greater cell adhesion and proliferation, while optimizing the osseointegration and healing processes. Other alternatives may play a more “active” role while promoting regeneration processes and controlling local infectious diseases or painful responses. In order to look for the best translational approach of the biomaterial, each option must be chosen with the correct diagnosis of the case to be treated. Universidad Nacional, Costa Rica 2019-12-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion text Documentos application/pdf text/html application/epub+zip https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284 10.15359/rcv.37-3.10 Ciencias Veterinarias; Vol. 37 No. 3 (2019): Suplement: First Symposium on Regenerative Medicine and Nanotechnology; 28 Ciencias Veterinarias; Vol. 37 Núm. 3 (2019): Suplemento: Simposio de Medicina Regenerativa y Nanotecnología; 28 2215-4507 0250-5649 eng https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284/18622 https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284/18681 https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284/18694 Copyright (c) 2019 Revista Ciencias Veterinarias
institution Universidad Nacional de Costa Rica
collection Ciencias Veterinarias
language eng
format Online
author Chavarría-Bolaños, Daniel
Villalobos, Diana
Vega-Baudrit, José Roberto
spellingShingle Chavarría-Bolaños, Daniel
Villalobos, Diana
Vega-Baudrit, José Roberto
3D polymeric scaffolds for oral tissue regeneration
author_facet Chavarría-Bolaños, Daniel
Villalobos, Diana
Vega-Baudrit, José Roberto
author_sort Chavarría-Bolaños, Daniel
title 3D polymeric scaffolds for oral tissue regeneration
title_short 3D polymeric scaffolds for oral tissue regeneration
title_full 3D polymeric scaffolds for oral tissue regeneration
title_fullStr 3D polymeric scaffolds for oral tissue regeneration
title_full_unstemmed 3D polymeric scaffolds for oral tissue regeneration
title_sort 3d polymeric scaffolds for oral tissue regeneration
title_alt Andamios poliméricos 3D para regeneración de tejido oral
publisher Universidad Nacional, Costa Rica
publishDate 2019
url https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/13284
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AT villalobosdiana 3dpolymericscaffoldsfororaltissueregeneration
AT vegabaudritjoseroberto 3dpolymericscaffoldsfororaltissueregeneration
AT chavarriabolanosdaniel andamiospolimericos3dpararegeneraciondetejidooral
AT villalobosdiana andamiospolimericos3dpararegeneraciondetejidooral
AT vegabaudritjoseroberto andamiospolimericos3dpararegeneraciondetejidooral
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