Medroxyprogesterone acetate in homemade intravaginal devices for estrus synchronization in hair ewes: Evaluation of efficacy, adverse effects and comparison with a commercial device in Costa Rican herds.

Medroxyprogesterone acetate in homemade intravaginal devices for estrus synchronization in hair ewes: Evaluation of efficacy, adverse effects and comparison with a commercial device in Costa Rican herds.

Detalles Bibliográficos
Autores principales: González, Silvia, Luna-Tortós, Carlos
Formato: Online
Idioma:spa
Publicado: Universidad Nacional, Costa Rica 2017
Acceso en línea:https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/10094
id VETERINARIA10094
record_format ojs
institution Universidad Nacional de Costa Rica
collection Ciencias Veterinarias
language spa
format Online
author González, Silvia
Luna-Tortós, Carlos
spellingShingle González, Silvia
Luna-Tortós, Carlos
Medroxyprogesterone acetate in homemade intravaginal devices for estrus synchronization in hair ewes: Evaluation of efficacy, adverse effects and comparison with a commercial device in Costa Rican herds.
author_facet González, Silvia
Luna-Tortós, Carlos
author_sort González, Silvia
title Medroxyprogesterone acetate in homemade intravaginal devices for estrus synchronization in hair ewes: Evaluation of efficacy, adverse effects and comparison with a commercial device in Costa Rican herds.
title_short Medroxyprogesterone acetate in homemade intravaginal devices for estrus synchronization in hair ewes: Evaluation of efficacy, adverse effects and comparison with a commercial device in Costa Rican herds.
title_full Medroxyprogesterone acetate in homemade intravaginal devices for estrus synchronization in hair ewes: Evaluation of efficacy, adverse effects and comparison with a commercial device in Costa Rican herds.
title_fullStr Medroxyprogesterone acetate in homemade intravaginal devices for estrus synchronization in hair ewes: Evaluation of efficacy, adverse effects and comparison with a commercial device in Costa Rican herds.
title_full_unstemmed Medroxyprogesterone acetate in homemade intravaginal devices for estrus synchronization in hair ewes: Evaluation of efficacy, adverse effects and comparison with a commercial device in Costa Rican herds.
title_sort medroxyprogesterone acetate in homemade intravaginal devices for estrus synchronization in hair ewes: evaluation of efficacy, adverse effects and comparison with a commercial device in costa rican herds.
title_alt Medroxiprogesterona acetato para la elaboración de dispositivos intravaginales caseros usados en la sincronización del estro en ovinos de pelo: Evaluación de su eficacia, sus efectos secundarios y comparación con un dispositivo comercial en hatos de Costa Rica.
publisher Universidad Nacional, Costa Rica
publishDate 2017
url https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/10094
work_keys_str_mv AT gonzalezsilvia medroxyprogesteroneacetateinhomemadeintravaginaldevicesforestrussynchronizationinhairewesevaluationofefficacyadverseeffectsandcomparisonwithacommercialdeviceincostaricanherds
AT lunatortoscarlos medroxyprogesteroneacetateinhomemadeintravaginaldevicesforestrussynchronizationinhairewesevaluationofefficacyadverseeffectsandcomparisonwithacommercialdeviceincostaricanherds
AT gonzalezsilvia medroxiprogesteronaacetatoparalaelaboraciondedispositivosintravaginalescaserosusadosenlasincronizaciondelestroenovinosdepeloevaluaciondesueficaciasusefectossecundariosycomparacionconundispositivocomercialenhatosdecostarica
AT lunatortoscarlos medroxiprogesteronaacetatoparalaelaboraciondedispositivosintravaginalescaserosusadosenlasincronizaciondelestroenovinosdepeloevaluaciondesueficaciasusefectossecundariosycomparacionconundispositivocomercialenhatosdecostarica
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spelling VETERINARIA100942019-08-27T15:20:43Z Medroxyprogesterone acetate in homemade intravaginal devices for estrus synchronization in hair ewes: Evaluation of efficacy, adverse effects and comparison with a commercial device in Costa Rican herds. Medroxiprogesterona acetato para la elaboración de dispositivos intravaginales caseros usados en la sincronización del estro en ovinos de pelo: Evaluación de su eficacia, sus efectos secundarios y comparación con un dispositivo comercial en hatos de Costa Rica. González, Silvia Luna-Tortós, Carlos Sincronización del estro ovinos medroxiprogesterona acetato estrus synchronization ewes medroxyprogesterone acetate The goal of our study was to determine the pharmacological efficacy and adverse effects of a homemade intravaginal device containing medroxyprogesterone acetate for estrus synchronization in hair ewes. A total of 78 adult, multiparous, cycling females were included in the two-phase experiment. During the first phase 18 ewes were included, and the efficacy and adverse effects of the homemade device were evaluated. In the second phase 60 ewes were aleatory assigned into two experimental groups: (G1) homemade intravaginal device (n-30), and (G2) commercial device (n-30) with the goal of comparing the estrus synchronization rate and conception rate among groups when using natural mating. The protocol consisted of 12-days treatment with 60mg of medroxyprogesterone acetate (MAP) by using the intravaginal device, followed by 200 UI eCG and 5 mg dinoprost tromethamine injection on day 12. A total of 13 males were tested by complete andrological evaluation, 8 were included as satisfactory males for the experiments. During both phases no signs of estrus were observed during the treatment with MAP, and 100% showed estrous signs 48 hours after device withdrawal. Adverse effects observed in the first part included: Mild vaginitis in all ewes, 3 females presented adherences, 2 showed fibrinogen increase at day 12, and a general lower leucocyte count after treatment was observed. In the second phase, no differences in estrus synchronization was observed among groups, and conception rates were 80.0% and 76.7% for G1 and G2 respectively. We conclude that the homemade intravaginal device is as effective as a commercial one for estrus synchronization, which allows obtaining high pregnancy rates in hairy sheep in Costa Rica. El objetivo del trabajo fue determinar la eficacia farmacológica y los efectos secundarios de un dispositivo intravaginal de fabricación casera elaborado con acetato de medroxiprogestrona para la sincronización del estro en ovinos de pelo. Se incluyeron un total de 78 hembras adultas, multíparas y ciclando en un estudio de dos etapas. En la primera etapa se utilizaron 18 animales con el objetivo de analizar la eficacia y los efectos secundarios del dispositivo de elaboración casera. En la segunda etapa se utilizaron 60 hembras divididas aleatoriamente en dos grupos: (G1) dispositivo casero (n-30), (G2) dispositivo comercial (n-30). El fin de esta etapa fue comparar la tasa de sincronización de celos y la tasa de concepción por monta natural. Para la sincronización se colocó el dispositivo con 60mg de acetato de medroxiprogesterona durante 12 días, con inyección de 200 UI de eCG y 5 mg de dinoprost trometamina. Se evaluaron andrológicamente 13 machos, de los cuales 4 fueron descartados por ser insatisfactorios y se utilizaron 8 machos satisfactorios durante ambas fases del estudio. En ambas etapas la presentación de celo fue nula durante la presencia del dispositivo y 100% presentaron celo 48 horas después de su retiro. Los efectos adversos en la primera etapa fueron: Vaginitis leve al día 12 en todas las hembras, 3 presentaron adherencias, 2 hembras con aumento de fibrinógeno el día 12 y una disminución general de los leucocitos. En la segunda etapa no hubo diferencias en la sincronización entre los grupos, la tasa de concepción fue de 80,0% y 76,7% en G1 y G2, respectivamente. Basado en los resultados de este trabajo, el dispositivo intravaginal de fabricación casera es efectivo para la sincronización del estro en ovinos de pelo y para la obtención de altas tasas de preñez por monta natural. Universidad Nacional, Costa Rica 2017-12-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/html https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/10094 10.15359/rcv.35-2.3 Ciencias Veterinarias; Vol. 35 No. 2 (2017): Ciencias Veterinarias Vol. 35, No. 2, 2017: July-December; 85-102 Ciencias Veterinarias; Vol. 35 Núm. 2 (2017): Ciencias Veterinarias (Julio-Diciembre); 85-102 2215-4507 0250-5649 spa https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/10094/12398 https://www.revistas.una.ac.cr/index.php/veterinaria/article/view/10094/12485 Copyright (c) 2017 Revista Ciencias Veterinarias

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