Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response
| Autores principales: | , , , |
|---|---|
| Formato: | Online |
| Idioma: | eng |
| Publicado: |
Universidad de Costa Rica
2007
|
| Acceso en línea: | https://revistas.ucr.ac.cr/index.php/rbt/article/view/6061 |
| id |
RBT6061 |
|---|---|
| record_format |
ojs |
| spelling |
RBT60612022-05-30T19:06:49Z Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response Chaves, Fernando Chacón, Mauricio Badilla, Beatriz Arévalo, Carolina Echinacea purpurea propiedades inmunoestimulatorias extracto de plantas linfoproliferación in vitro anticuerpos de anti-veneno murino immunostimulatory properties adjuvant plant extract in vitro lymphoproliferation murine antivenom antibodies The effect of aqueous extract of Echinacea purpurea roots on the murine antibody response to Bothrops asper snake venom in vivo was studied. Three groups were used. Group #1, baseline control, was treated with snake venom plus PBS. Group #2 was treated with snake venom plus sodium alginate as adjuvant (routine method used at Instituto Clodomiro Picado), and group #3 or experimental group, was treated with snake venom plus aqueous extract of E. purpurea root as adjuvant. In all groups, the first inoculation was done with Freund's complete adjuvant (FCA). By the time of the second bleeding, mice in group #3 showed a remarkable increment in the level of anti-venom antibodies compared with those in groups #1 or #2. In vitro immune cell proliferation as a response to aqueous extract of E. purpurea root was studied using human lymphocytes activated with different lectins (Con A, PHA and PWM). In all cases, increase in percentage of lymphoproliferation was greater when E. purpurea root extract was used in addition to individual lectins. Universidad de Costa Rica 2007-03-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Article Text application/pdf https://revistas.ucr.ac.cr/index.php/rbt/article/view/6061 10.15517/rbt.v55i1.6061 Revista de Biología Tropical; Vol. 55 No. 1 (2007): Volume 55 – Regular number 1 – March 2007; 113–119 Revista de Biología Tropical; Vol. 55 Núm. 1 (2007): Volumen 55 – Número regular 1 – Marzo 2007; 113–119 Revista Biología Tropical; Vol. 55 N.º 1 (2007): Volume 55 – Regular number 1 – March 2007; 113–119 2215-2075 0034-7744 10.15517/rbt.v55i1 eng https://revistas.ucr.ac.cr/index.php/rbt/article/view/6061/5766 Copyright (c) 2007 Revista de Biología Tropical http://creativecommons.org/licenses/by/4.0 |
| institution |
Universidad de Costa Rica |
| collection |
Revista de Biología Tropical |
| language |
eng |
| format |
Online |
| author |
Chaves, Fernando Chacón, Mauricio Badilla, Beatriz Arévalo, Carolina |
| spellingShingle |
Chaves, Fernando Chacón, Mauricio Badilla, Beatriz Arévalo, Carolina Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response |
| author_facet |
Chaves, Fernando Chacón, Mauricio Badilla, Beatriz Arévalo, Carolina |
| author_sort |
Chaves, Fernando |
| title |
Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response |
| title_short |
Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response |
| title_full |
Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response |
| title_fullStr |
Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response |
| title_full_unstemmed |
Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response |
| title_sort |
effect of echinacea purpurea (asteraceae) aqueous extract on antibody response to bothrops asper venom and immune cell response |
| title_alt |
Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response |
| publisher |
Universidad de Costa Rica |
| publishDate |
2007 |
| url |
https://revistas.ucr.ac.cr/index.php/rbt/article/view/6061 |
| work_keys_str_mv |
AT chavesfernando effectofechinaceapurpureaasteraceaeaqueousextractonantibodyresponsetobothropsaspervenomandimmunecellresponse AT chaconmauricio effectofechinaceapurpureaasteraceaeaqueousextractonantibodyresponsetobothropsaspervenomandimmunecellresponse AT badillabeatriz effectofechinaceapurpureaasteraceaeaqueousextractonantibodyresponsetobothropsaspervenomandimmunecellresponse AT arevalocarolina effectofechinaceapurpureaasteraceaeaqueousextractonantibodyresponsetobothropsaspervenomandimmunecellresponse |
| _version_ |
1810114587569160192 |