Adverse reactions from community directed treatment with ivermectin (CDTI ) for onchocerciasis and loiasis in Ondo State, Nigeria
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| Formato: | Online |
| Idioma: | eng |
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Universidad de Costa Rica
2008
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| Acceso en línea: | https://revistas.ucr.ac.cr/index.php/rbt/article/view/5750 |
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RBT5750 |
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RBT57502022-06-06T18:05:27Z Adverse reactions from community directed treatment with ivermectin (CDTI ) for onchocerciasis and loiasis in Ondo State, Nigeria Adverse reactions from community directed treatment with ivermectin (CDTI ) for onchocerciasis and loiasis in Ondo State, Nigeria Otubanjo, O.A. Adeoye, G.O. Ibidapo, C.A. Akinsanya, B. Okeke, P. Atalabi, T Adejai, E.T. Braide, E. Oncocercosis loiasis reacciones adversas ivermectina procedimiento de evaluación rápida para Loa loa Programa Africano para el Control de Oncocercosis Onchocerciasis adverse reactions community directed treatment with ivermectin rapid assessment procedure for Loa loa African Programme for Onchocerciasis Control Onchocerciasis is an endemic disease in Ondo state, Nigeria. Community directed distribution of ivermectin is currently on-going in some local government areas of the state. Randomly selected persons (2,331 males and 2,469 females) were interviewed using a modified rapid assessment procedure for Loa loa (RAPLOA) to assess community directed treatment with ivermectin. The retrospective study evaluated the coverage, impacts and adverse reactions to the drug treatment. A questionnaire was administered by house-to-house visit in six local government areas, implementing community directed treatment with ivermectin (CDTI) in this bioclimatic zone. A total of 2,398 respondents were reported to have participated in the treatment. The overall ivermectin coverage of 49.96% was recorded (range 0 - 52% in different communities). Adverse reactions from ivermectin administration were experienced in 38% of individuals. Diverse adverse reactions experienced included predominantly itching (18.50%); oedema, especially of the face and the limbs (8.2%); rashes (3.4%) and body weakness (2.4%). Expulsion of intestinal worms occurred in 0.96% of the respondents. The occurrence of adverse reactions in relation to age categories was statistically significant. Neither fatal nor severe adverse reactions were reported by respondents. Significantly, despite experienced adverse reactions, continued participation, acceptability and compliance to ivermectin treatment was expressed by the various communities. This attitude is in consonance with the African Programme for Onchocerciasis Control (APOC) objectives. Universidad de Costa Rica 2008-12-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Article Text application/pdf https://revistas.ucr.ac.cr/index.php/rbt/article/view/5750 10.15517/rbt.v56i4.5750 Revista de Biología Tropical; Vol. 56 No. 4 (2008): Volume 56 – Regular number 4 – December 2008; 1635–1643 Revista de Biología Tropical; Vol. 56 Núm. 4 (2008): Volumen 56 – Número regular 4 – Diciembre 2008; 1635–1643 Revista Biología Tropical; Vol. 56 N.º 4 (2008): Volume 56 – Regular number 4 – December 2008; 1635–1643 2215-2075 0034-7744 10.15517/rbt.v56i4 eng https://revistas.ucr.ac.cr/index.php/rbt/article/view/5750/5491 Copyright (c) 2008 Revista de Biología Tropical http://creativecommons.org/licenses/by/4.0 |
| institution |
Universidad de Costa Rica |
| collection |
Revista de Biología Tropical |
| language |
eng |
| format |
Online |
| author |
Otubanjo, O.A. Adeoye, G.O. Ibidapo, C.A. Akinsanya, B. Okeke, P. Atalabi, T Adejai, E.T. Braide, E. |
| spellingShingle |
Otubanjo, O.A. Adeoye, G.O. Ibidapo, C.A. Akinsanya, B. Okeke, P. Atalabi, T Adejai, E.T. Braide, E. Adverse reactions from community directed treatment with ivermectin (CDTI ) for onchocerciasis and loiasis in Ondo State, Nigeria |
| author_facet |
Otubanjo, O.A. Adeoye, G.O. Ibidapo, C.A. Akinsanya, B. Okeke, P. Atalabi, T Adejai, E.T. Braide, E. |
| author_sort |
Otubanjo, O.A. |
| title |
Adverse reactions from community directed treatment with ivermectin (CDTI ) for onchocerciasis and loiasis in Ondo State, Nigeria |
| title_short |
Adverse reactions from community directed treatment with ivermectin (CDTI ) for onchocerciasis and loiasis in Ondo State, Nigeria |
| title_full |
Adverse reactions from community directed treatment with ivermectin (CDTI ) for onchocerciasis and loiasis in Ondo State, Nigeria |
| title_fullStr |
Adverse reactions from community directed treatment with ivermectin (CDTI ) for onchocerciasis and loiasis in Ondo State, Nigeria |
| title_full_unstemmed |
Adverse reactions from community directed treatment with ivermectin (CDTI ) for onchocerciasis and loiasis in Ondo State, Nigeria |
| title_sort |
adverse reactions from community directed treatment with ivermectin (cdti ) for onchocerciasis and loiasis in ondo state, nigeria |
| title_alt |
Adverse reactions from community directed treatment with ivermectin (CDTI ) for onchocerciasis and loiasis in Ondo State, Nigeria |
| publisher |
Universidad de Costa Rica |
| publishDate |
2008 |
| url |
https://revistas.ucr.ac.cr/index.php/rbt/article/view/5750 |
| work_keys_str_mv |
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