Increase of sulfadiazine effect against Toxoplasma gondii by using watermelon or cantaloupe seeds
In an experimental model the anti-Toxoplasma effect of watermelon and cantaloupe seeds, together with sulfadiazine (Sd7.5 and Sd 15) given by oral route, were studied. Combination of any of these seeds with the drug was able to increase the survival time and cure sorne tachyzoite infected mice. The...
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Universidad de Costa Rica
1990
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Acceso en línea: | https://revistas.ucr.ac.cr/index.php/rbt/article/view/25052 |
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RBT250522023-09-06T17:38:41Z Increase of sulfadiazine effect against Toxoplasma gondii by using watermelon or cantaloupe seeds Increase of sulfadiazine effect against Toxoplasma gondii by using watermelon or cantaloupe seeds Chinchilla, M Marin, R Catarinella, G In an experimental model the anti-Toxoplasma effect of watermelon and cantaloupe seeds, together with sulfadiazine (Sd7.5 and Sd 15) given by oral route, were studied. Combination of any of these seeds with the drug was able to increase the survival time and cure sorne tachyzoite infected mice. The effect was produced either by peeled or complete seeds and more significant results were obtained when Sd7.5 and 103 tachyzoite inoculum was used in the model. Sorne Toxoplasma oocyst infected mice were cured with the seeds alone (75% for watermelon, 37,5 or 50% for cantaloupe. Body weight variations are independent of the treatment with Sd alone or in combination with watermeIon or cantaloupe seeds. In an experimental model the anti-Toxoplasma effect of watermelon and cantaloupe seeds, together with sulfadiazine (Sd7.5 and Sd 15) given by oral route, were studied. Combination of any of these seeds with the drug was able to increase the survival time and cure sorne tachyzoite infected mice. The effect was produced either by peeled or complete seeds and more significant results were obtained when Sd7.5 and 103 tachyzoite inoculum was used in the model. Sorne Toxoplasma oocyst infected mice were cured with the seeds alone (75% for watermelon, 37,5 or 50% for cantaloupe. Body weight variations are independent of the treatment with Sd alone or in combination with watermeIon or cantaloupe seeds. Universidad de Costa Rica 1990-11-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Article application/pdf https://revistas.ucr.ac.cr/index.php/rbt/article/view/25052 Revista de Biología Tropical; Vol. 38 No. 2A (1990): Volume 38 – Regular number 2A – November 1990; 235–241 Revista de Biología Tropical; Vol. 38 Núm. 2A (1990): Volumen 38 – Número regular 2A – Noviembre 1990; 235–241 Revista Biología Tropical; Vol. 38 N.º 2A (1990): Volume 38 – Regular number 2A – November 1990; 235–241 2215-2075 0034-7744 10.15517/rbt.v38i2 eng https://revistas.ucr.ac.cr/index.php/rbt/article/view/25052/25299 Copyright (c) 1990 Revista de Biología Tropical http://creativecommons.org/licenses/by/4.0 |
institution |
Universidad de Costa Rica |
collection |
Revista de Biología Tropical |
language |
eng |
format |
Online |
author |
Chinchilla, M Marin, R Catarinella, G |
spellingShingle |
Chinchilla, M Marin, R Catarinella, G Increase of sulfadiazine effect against Toxoplasma gondii by using watermelon or cantaloupe seeds |
author_facet |
Chinchilla, M Marin, R Catarinella, G |
author_sort |
Chinchilla, M |
description |
In an experimental model the anti-Toxoplasma effect of watermelon and cantaloupe seeds, together with sulfadiazine (Sd7.5 and Sd 15) given by oral route, were studied. Combination of any of these seeds with the drug was able to increase the survival time and cure sorne tachyzoite infected mice. The effect was produced either by peeled or complete seeds and more significant results were obtained when Sd7.5 and 103 tachyzoite inoculum was used in the model. Sorne Toxoplasma oocyst infected mice were cured with the seeds alone (75% for watermelon, 37,5 or 50% for cantaloupe. Body weight variations are independent of the treatment with Sd alone or in combination with watermeIon or cantaloupe seeds. |
title |
Increase of sulfadiazine effect against Toxoplasma gondii by using watermelon or cantaloupe seeds |
title_short |
Increase of sulfadiazine effect against Toxoplasma gondii by using watermelon or cantaloupe seeds |
title_full |
Increase of sulfadiazine effect against Toxoplasma gondii by using watermelon or cantaloupe seeds |
title_fullStr |
Increase of sulfadiazine effect against Toxoplasma gondii by using watermelon or cantaloupe seeds |
title_full_unstemmed |
Increase of sulfadiazine effect against Toxoplasma gondii by using watermelon or cantaloupe seeds |
title_sort |
increase of sulfadiazine effect against toxoplasma gondii by using watermelon or cantaloupe seeds |
title_alt |
Increase of sulfadiazine effect against Toxoplasma gondii by using watermelon or cantaloupe seeds |
publisher |
Universidad de Costa Rica |
publishDate |
1990 |
url |
https://revistas.ucr.ac.cr/index.php/rbt/article/view/25052 |
work_keys_str_mv |
AT chinchillam increaseofsulfadiazineeffectagainsttoxoplasmagondiibyusingwatermelonorcantaloupeseeds AT marinr increaseofsulfadiazineeffectagainsttoxoplasmagondiibyusingwatermelonorcantaloupeseeds AT catarinellag increaseofsulfadiazineeffectagainsttoxoplasmagondiibyusingwatermelonorcantaloupeseeds |
_version_ |
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