Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in Sprague-Dawley rats

The anti-inflamrnatory properties of Loasa specic¡sa and Loasa triphylla (Loasaceae), Urtica leptuphylla and Urera baccifera (Urticaceae), and Chaptalia nutans (Astemceae) were studied using the carregeenan induced mt paw edema model. Aqueous extmcts of each plant were made according to the ethnobor...

Full description

Bibliographic Details
Main Authors:	Badilla, Beatriz, Mora, Gerardo, Poveda, Luis Jorge
Format:	Online
Language:	eng
Published:	Universidad de Costa Rica 1999
Online Access:	https://revistas.ucr.ac.cr/index.php/rbt/article/view/19229

id	RBT19229
record_format	ojs
spelling	RBT192292022-05-25T21:20:20Z Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in 8prague-Dawley rats Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in Sprague-Dawley rats Badilla, Beatriz Mora, Gerardo Poveda, Luis Jorge medicinal plants anti-inflarnmmatory agent edema urticaceae asteraceae loasaceae The anti-inflamrnatory properties of Loasa specic¡sa and Loasa triphylla (Loasaceae), Urtica leptuphylla and Urera baccifera (Urticaceae), and Chaptalia nutans (Astemceae) were studied using the carregeenan induced mt paw edema model. Aqueous extmcts of each plant were made according to the ethnoboranical use. The hippocratic assay was made with female mts; the dose used was 500 mglkg i.p. andthe control group received 0.5 mi of n.s.s .. A11 the lmimals treated showed hipothermia, and those treated with the extmcts of Chaptalia nutans, Urera baccifera and Urtica lept/lPhylla showed an increased colinergic activity. Acute toxicities of !he aqueous extmcts were studied in mice an tbe mean lethal doses ranged between 1.0226 and 1.2022 glkg. The extracts of Urera baccifera, Chaptalia nutans, Loasa speciosa and Loasa triphylla (500 mglkg i.p.) showed an antiinflarnmatory activity compamble with that of indomethacin. The extracts of U. baccifera and C. nutans, which showed the gI"tatest anti-inflamrtJatory activity, did not show it when used orally (500 mg/k:g p.o.). The anti-inflamrnatory properties of Loasa specic¡sa and Loasa triphylla (Loasaceae), Urtica leptuphylla and Urera baccifera (Urticaceae), and Chaptalia nutans (Astemceae) were studied using the carregeenan induced mt paw edema model. Aqueous extmcts of each plant were made according to the ethnoboranical use. The hippocratic assay was made with female mts; the dose used was 500 mglkg i.p. andthe control group received 0.5 mi of n.s.s .. A11 the lmimals treated showed hipothermia, and those treated with the extmcts of Chaptalia nutans, Urera baccifera and Urtica lept/lPhylla showed an increased colinergic activity. Acute toxicities of !he aqueous extmcts were studied in mice an tbe mean lethal doses ranged between 1.0226 and 1.2022 glkg. The extracts of Urera baccifera, Chaptalia nutans, Loasa speciosa and Loasa triphylla (500 mglkg i.p.) showed an antiinflarnmatory activity compamble with that of indomethacin. The extracts of U. baccifera and C. nutans, which showed the gI"tatest anti-inflamrtJatory activity, did not show it when used orally (500 mg/k:g p.o.). Universidad de Costa Rica 1999-03-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Article application/pdf https://revistas.ucr.ac.cr/index.php/rbt/article/view/19229 10.15517/rbt.v47i4.19229 Revista de Biología Tropical; Vol. 47 No. 4 (1999): Volume 47 – Regular number 4 – December 1999; 723–727 Revista de Biología Tropical; Vol. 47 Núm. 4 (1999): Volumen 47 – Volumen regular 4 – Diciembre 1999; 723–727 Revista Biología Tropical; Vol. 47 N.º 4 (1999): Volume 47 – Regular number 4 – December 1999; 723–727 2215-2075 0034-7744 10.15517/rbt.v47i4 eng https://revistas.ucr.ac.cr/index.php/rbt/article/view/19229/26034 Copyright (c) 1999 Revista de Biología Tropical http://creativecommons.org/licenses/by/4.0
institution	Universidad de Costa Rica
collection	Revista de Biología Tropical
language	eng
format	Online
author	Badilla, Beatriz Mora, Gerardo Poveda, Luis Jorge
spellingShingle	Badilla, Beatriz Mora, Gerardo Poveda, Luis Jorge Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in Sprague-Dawley rats
author_facet	Badilla, Beatriz Mora, Gerardo Poveda, Luis Jorge
author_sort	Badilla, Beatriz
description	The anti-inflamrnatory properties of Loasa specic¡sa and Loasa triphylla (Loasaceae), Urtica leptuphylla and Urera baccifera (Urticaceae), and Chaptalia nutans (Astemceae) were studied using the carregeenan induced mt paw edema model. Aqueous extmcts of each plant were made according to the ethnoboranical use. The hippocratic assay was made with female mts; the dose used was 500 mglkg i.p. andthe control group received 0.5 mi of n.s.s .. A11 the lmimals treated showed hipothermia, and those treated with the extmcts of Chaptalia nutans, Urera baccifera and Urtica lept/lPhylla showed an increased colinergic activity. Acute toxicities of !he aqueous extmcts were studied in mice an tbe mean lethal doses ranged between 1.0226 and 1.2022 glkg. The extracts of Urera baccifera, Chaptalia nutans, Loasa speciosa and Loasa triphylla (500 mglkg i.p.) showed an antiinflarnmatory activity compamble with that of indomethacin. The extracts of U. baccifera and C. nutans, which showed the gI"tatest anti-inflamrtJatory activity, did not show it when used orally (500 mg/k:g p.o.).
title	Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in Sprague-Dawley rats
title_short	Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in Sprague-Dawley rats
title_full	Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in Sprague-Dawley rats
title_fullStr	Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in Sprague-Dawley rats
title_full_unstemmed	Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in Sprague-Dawley rats
title_sort	anti-inflammatory activity of aqueous extracts of ove costa rican medicinalplants in sprague-dawley rats
title_alt	Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in 8prague-Dawley rats
publisher	Universidad de Costa Rica
publishDate	1999
url	https://revistas.ucr.ac.cr/index.php/rbt/article/view/19229
work_keys_str_mv	AT badillabeatriz antiinflammatoryactivityofaqueousextractsofovecostaricanmedicinalplantsin8praguedawleyrats AT moragerardo antiinflammatoryactivityofaqueousextractsofovecostaricanmedicinalplantsin8praguedawleyrats AT povedaluisjorge antiinflammatoryactivityofaqueousextractsofovecostaricanmedicinalplantsin8praguedawleyrats AT badillabeatriz antiinflammatoryactivityofaqueousextractsofovecostaricanmedicinalplantsinspraguedawleyrats AT moragerardo antiinflammatoryactivityofaqueousextractsofovecostaricanmedicinalplantsinspraguedawleyrats AT povedaluisjorge antiinflammatoryactivityofaqueousextractsofovecostaricanmedicinalplantsinspraguedawleyrats
_version_	1810114781868195840

Anti-inflammatory activity of aqueous extracts of Ove Costa Rican medicinalplants in Sprague-Dawley rats

Similar Items