Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides

Pesticides have been widely used in developing countries over the years. A large amount of these remains in the environment and organisms. Pesticide pollution is detrimental to human health. The effects can be seen on a short or a long-term basis and the symptoms can vary from headache to cancer. On...

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Autores principales:	Ramírez, Vanessa, Cuenca, Patricia
Formato:	Online
Idioma:	eng
Publicado:	Universidad de Costa Rica 2001
Acceso en línea:	https://revistas.ucr.ac.cr/index.php/rbt/article/view/16730

id	RBT16730
record_format	ojs
spelling	RBT167302022-05-25T21:32:36Z Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides Ramírez, Vanessa Cuenca, Patricia micronuclei lymphocytes pesticides human population biomonitoring banana workers women Pesticides have been widely used in developing countries over the years. A large amount of these remains in the environment and organisms. Pesticide pollution is detrimental to human health. The effects can be seen on a short or a long-term basis and the symptoms can vary from headache to cancer. Only a minority of studies focuses on their genotoxic effect. This study assesses the genotoxic effect of the pesticides used at banana-packaging plants with binucleate micronuclei assay using cultured lymphocytes. The studied population included 32 exposed and 37 unexposed women from Costa Rica. There is no significant difference between the two groups. However, women who worked at the packaging plant and had stillbirths or spontaneous abortions were 1.45 times more (α = 0.06) likely to have an increased micronuclei frequency than their coworkers who lacked those disorders; this may indicate genetic susceptibility. In vitro pesticides studies and susceptibility biomarkers are needed to identify subgroups with higher risks. Pesticides have been widely used in developing countries over the years. A large amount of these remains in the environment and organisms. Pesticide pollution is detrimental to human health. The effects can be seen on a short or a long-term basis and the symptoms can vary from headache to cancer. Only a minority of studies focuses on their genotoxic effect. This study assesses the genotoxic effect of the pesticides used at banana-packaging plants with binucleate micronuclei assay using cultured lymphocytes. The studied population included 32 exposed and 37 unexposed women from Costa Rica. There is no significant difference between the two groups. However, women who worked at the packaging plant and had stillbirths or spontaneous abortions were 1.45 times more (α = 0.06) likely to have an increased micronuclei frequency than their coworkers who lacked those disorders; this may indicate genetic susceptibility. In vitro pesticides studies and susceptibility biomarkers are needed to identify subgroups with higher risks. Universidad de Costa Rica 2001-03-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Article application/pdf https://revistas.ucr.ac.cr/index.php/rbt/article/view/16730 Revista de Biología Tropical; Vol. 49 No. 1 (2001): Volume 49 – Regular number 1 – March 2001; 1–8 Revista de Biología Tropical; Vol. 49 Núm. 1 (2001): Volumen 49 – Número regular 1 – Marzo 2001; 1–8 Revista Biología Tropical; Vol. 49 N.º 1 (2001): Volume 49 – Regular number 1 – March 2001; 1–8 2215-2075 0034-7744 10.15517/rbt.v49i1 eng https://revistas.ucr.ac.cr/index.php/rbt/article/view/16730/16228 Copyright (c) 2001 Revista de Biología Tropical http://creativecommons.org/licenses/by/4.0
institution	Universidad de Costa Rica
collection	Revista de Biología Tropical
language	eng
format	Online
author	Ramírez, Vanessa Cuenca, Patricia
spellingShingle	Ramírez, Vanessa Cuenca, Patricia Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides
author_facet	Ramírez, Vanessa Cuenca, Patricia
author_sort	Ramírez, Vanessa
description	Pesticides have been widely used in developing countries over the years. A large amount of these remains in the environment and organisms. Pesticide pollution is detrimental to human health. The effects can be seen on a short or a long-term basis and the symptoms can vary from headache to cancer. Only a minority of studies focuses on their genotoxic effect. This study assesses the genotoxic effect of the pesticides used at banana-packaging plants with binucleate micronuclei assay using cultured lymphocytes. The studied population included 32 exposed and 37 unexposed women from Costa Rica. There is no significant difference between the two groups. However, women who worked at the packaging plant and had stillbirths or spontaneous abortions were 1.45 times more (α = 0.06) likely to have an increased micronuclei frequency than their coworkers who lacked those disorders; this may indicate genetic susceptibility. In vitro pesticides studies and susceptibility biomarkers are needed to identify subgroups with higher risks.
title	Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides
title_short	Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides
title_full	Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides
title_fullStr	Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides
title_full_unstemmed	Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides
title_sort	micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides
title_alt	Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides
publisher	Universidad de Costa Rica
publishDate	2001
url	https://revistas.ucr.ac.cr/index.php/rbt/article/view/16730
work_keys_str_mv	AT ramirezvanessa micronucleifrequencyinlymphocytesofindividualsoccupationallyexposedtopesticides AT cuencapatricia micronucleifrequencyinlymphocytesofindividualsoccupationallyexposedtopesticides
_version_	1810114726578880512

Micronuclei frequency in lymphocytes of individuals occupationally exposed to pesticides

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