Trombocitopenia versus SOFA parapredecir mortalidad en pacientescon sepsis en la Unidad de CuidadosIntensivos de un hospital de tercer nivelde Guatemala

e most common coagulation disorder in the intensive care unit isthrombocytopenia. Considering the fundamental role of platelets in hemostasis andas markers of disseminated intravascular coagulation, a significant decrease in plateletcounts is alarming in the context of septic patients, a...

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Autores principales:	Escobar Jimenez, Nancy; Facultad de Ciencias Medica, Universidad de San Carlos de Guatemala, Ranero Meneses, Jorge; Instituto Guatemalteco de Seguridad Social, Guatemala, Chocó-Cedillos, Andre; Unidad de atención integral del VIH y las infecciones crónicas, Hospital Roosevelt
Formato:	Online
Idioma:	spa
Publicado:	Universidad de San Carlos de Guatemala 2019
Acceso en línea:	http://www.revistasguatemala.usac.edu.gt/index.php/qyf/article/view/1511

id	QYF1511
record_format	ojs
spelling	QYF15112021-03-05T15:00:29Z Trombocitopenia versus SOFA parapredecir mortalidad en pacientescon sepsis en la Unidad de CuidadosIntensivos de un hospital de tercer nivelde Guatemala Escobar Jimenez, Nancy; Facultad de Ciencias Medica, Universidad de San Carlos de Guatemala Ranero Meneses, Jorge; Instituto Guatemalteco de Seguridad Social, Guatemala Chocó-Cedillos, Andre; Unidad de atención integral del VIH y las infecciones crónicas, Hospital Roosevelt e most common coagulation disorder in the intensive care unit isthrombocytopenia. Considering the fundamental role of platelets in hemostasis andas markers of disseminated intravascular coagulation, a significant decrease in plateletcounts is alarming in the context of septic patients, and it is known to be a predictor ofdeath. The objective was to compare the ability of the platelet count with the SequentialOrgan Failure Assessment (SOFA) to predict death in patients with severe sepsis or septic shock. A longitudinal study was conducted with a sample of 29 consecutivecases evaluated during January to December 2015 in the Intensive Care Unit of theGeneral Hospital of Diseases (HGE) of the Guatemalan Social Security Institute.Platelet and SOFA counts were performed at the first and the fih day of hospitalization,documenting the outcome of the patients. 51.7% of the patients were men and 48.3%were women, with an average age of 62.0 (16.9) years, median SOFA on admission of10 units (Q1=4, Q3=14) and platelet median on admission of 196000 (Q1=100000,Q3=250000). e univariate association between thrombocytopenia and death wassignificant (p = .021, RR = 2.45, CI 95% [1.21, 4.99]). According to a Bootstrap test,there is no significant difference between the predictive capacity of SOFA and plateletcount (p = .965). It was concluded that the presence of thrombocytopenia is a simplepredictor of death in patients with severe sepsis or septic shock, with similar capacity to SOFA. Universidad de San Carlos de Guatemala Organ Dysfunction Scores, Platelet Count, Sepsis, Septic Shock 2019-11-28 info:eu-repo/semantics/article Artículo revisado por pares info:eu-repo/semantics/publishedVersion application/pdf http://www.revistasguatemala.usac.edu.gt/index.php/qyf/article/view/1511 Revista Científica de la Facultad de Ciencias Químicas y Farmacia; Vol 1, No 29 (2019) spa http://www.revistasguatemala.usac.edu.gt/index.php/qyf/article/view/1511/1314
institution	Universidad de San Carlos de Guatemala
collection	Revista Científica de la Facultad de Ciencias Químicas y Farmacia
language	spa
format	Online
author	Escobar Jimenez, Nancy; Facultad de Ciencias Medica, Universidad de San Carlos de Guatemala Ranero Meneses, Jorge; Instituto Guatemalteco de Seguridad Social, Guatemala Chocó-Cedillos, Andre; Unidad de atención integral del VIH y las infecciones crónicas, Hospital Roosevelt
spellingShingle	Escobar Jimenez, Nancy; Facultad de Ciencias Medica, Universidad de San Carlos de Guatemala Ranero Meneses, Jorge; Instituto Guatemalteco de Seguridad Social, Guatemala Chocó-Cedillos, Andre; Unidad de atención integral del VIH y las infecciones crónicas, Hospital Roosevelt Trombocitopenia versus SOFA parapredecir mortalidad en pacientescon sepsis en la Unidad de CuidadosIntensivos de un hospital de tercer nivelde Guatemala
author_facet	Escobar Jimenez, Nancy; Facultad de Ciencias Medica, Universidad de San Carlos de Guatemala Ranero Meneses, Jorge; Instituto Guatemalteco de Seguridad Social, Guatemala Chocó-Cedillos, Andre; Unidad de atención integral del VIH y las infecciones crónicas, Hospital Roosevelt
author_sort	Escobar Jimenez, Nancy; Facultad de Ciencias Medica, Universidad de San Carlos de Guatemala
description	e most common coagulation disorder in the intensive care unit isthrombocytopenia. Considering the fundamental role of platelets in hemostasis andas markers of disseminated intravascular coagulation, a significant decrease in plateletcounts is alarming in the context of septic patients, and it is known to be a predictor ofdeath. The objective was to compare the ability of the platelet count with the SequentialOrgan Failure Assessment (SOFA) to predict death in patients with severe sepsis or septic shock. A longitudinal study was conducted with a sample of 29 consecutivecases evaluated during January to December 2015 in the Intensive Care Unit of theGeneral Hospital of Diseases (HGE) of the Guatemalan Social Security Institute.Platelet and SOFA counts were performed at the first and the fih day of hospitalization,documenting the outcome of the patients. 51.7% of the patients were men and 48.3%were women, with an average age of 62.0 (16.9) years, median SOFA on admission of10 units (Q1=4, Q3=14) and platelet median on admission of 196000 (Q1=100000,Q3=250000). e univariate association between thrombocytopenia and death wassignificant (p = .021, RR = 2.45, CI 95% [1.21, 4.99]). According to a Bootstrap test,there is no significant difference between the predictive capacity of SOFA and plateletcount (p = .965). It was concluded that the presence of thrombocytopenia is a simplepredictor of death in patients with severe sepsis or septic shock, with similar capacity to SOFA.
title	Trombocitopenia versus SOFA parapredecir mortalidad en pacientescon sepsis en la Unidad de CuidadosIntensivos de un hospital de tercer nivelde Guatemala
title_short	Trombocitopenia versus SOFA parapredecir mortalidad en pacientescon sepsis en la Unidad de CuidadosIntensivos de un hospital de tercer nivelde Guatemala
title_full	Trombocitopenia versus SOFA parapredecir mortalidad en pacientescon sepsis en la Unidad de CuidadosIntensivos de un hospital de tercer nivelde Guatemala
title_fullStr	Trombocitopenia versus SOFA parapredecir mortalidad en pacientescon sepsis en la Unidad de CuidadosIntensivos de un hospital de tercer nivelde Guatemala
title_full_unstemmed	Trombocitopenia versus SOFA parapredecir mortalidad en pacientescon sepsis en la Unidad de CuidadosIntensivos de un hospital de tercer nivelde Guatemala
title_sort	trombocitopenia versus sofa parapredecir mortalidad en pacientescon sepsis en la unidad de cuidadosintensivos de un hospital de tercer nivelde guatemala
publisher	Universidad de San Carlos de Guatemala
publishDate	2019
url	http://www.revistasguatemala.usac.edu.gt/index.php/qyf/article/view/1511
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Trombocitopenia versus SOFA parapredecir mortalidad en pacientescon sepsis en la Unidad de CuidadosIntensivos de un hospital de tercer nivelde Guatemala

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