Quantification of Chemokine CCL5 in Patients with Diabetes Mellitus Type 2 and/or Chronic Periodontitis: Preliminary Study
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| Formato: | Online |
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Universidad de Costa Rica
2017
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| Acceso en línea: | https://revistas.ucr.ac.cr/index.php/Odontos/article/view/28052 |
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ODONTOS28052 |
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ODONTOS280522021-06-09T00:14:06Z Quantification of Chemokine CCL5 in Patients with Diabetes Mellitus Type 2 and/or Chronic Periodontitis: Preliminary Study Sansores-España DDS, Luis Carrillo-Avila DDS, MINE, Arelly Sauri-Esquivel DDS, MO, Eduardo Guzmán-Marín MD, MSc, PhD, Eugenia Hernández DDS, MSc, PhD, Marcela Pozos-Guillén DDS, MSc, PhD, Amaury Martínez-Aguilar DDS, MIS, Víctor CCL5 LUMINEX® assays Periodontitis Perio papers The purpose of the present study was to quantify the presence of chemokine CCL5 (RANTES) in gingival crevicular fluid (LCG) in patients with chronic periodontitis (PC) and / or type 2 diabetes mellitus (DM2). A comparative cross-sectional study was conducted in 40 patients. LCG was taken from periodontal pockets and gingival grooves from 4 patient groups (10 per study group); patients who received periodontal, antibiotic and anti-inflammatory treatment 6 months prior to the study or who had systemic disease other than DM2 were excluded. Concentrations of CCL5 were determined by LUMINEX® assays. Descriptive statistics, one-way ANOVA, Student's T, and Pearson's correlation were performed. The quantification of CCL5 was higher in the patients who presented both diseases, followed by the group with only PC, healthy and the group with only DM2. No significant difference was found between groups and there was no correlation between quantifications and glycemic indicators. Although the differences were not significant, the group of patients with both diseases had the highest CCL5 quantification. The expression of CCL5 in LGC should be considered as a potential inducer of periodontal destruction, its determination could be useful for monitoring the health/disease of periodontal tissues. Universidad de Costa Rica 2017-05-05 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Article clinical research application/pdf text/html https://revistas.ucr.ac.cr/index.php/Odontos/article/view/28052 10.15517/ijds.v19i2.28052 Odovtos - International Journal of Dental Sciences; Vol. 19 No. 2 (2017): (May-August) Odovtos-International Journal of Dental Sciences; 71-78 Odovtos International Journal of Dental Sciences; Vol. 19 Núm. 2 (2017): (May-August) Odovtos-International Journal of Dental Sciences; 71-78 2215-3411 1659-1046 10.15517/ijds.v19i2 eng https://revistas.ucr.ac.cr/index.php/Odontos/article/view/28052/28142 https://revistas.ucr.ac.cr/index.php/Odontos/article/view/28052/29202 Copyright (c) 2017 Odovtos - International Journal of Dental Sciences |
| institution |
Universidad de Costa Rica |
| collection |
Odovtos International Journal of Dental Sciences |
| language |
eng |
| format |
Online |
| author |
Sansores-España DDS, Luis Carrillo-Avila DDS, MINE, Arelly Sauri-Esquivel DDS, MO, Eduardo Guzmán-Marín MD, MSc, PhD, Eugenia Hernández DDS, MSc, PhD, Marcela Pozos-Guillén DDS, MSc, PhD, Amaury Martínez-Aguilar DDS, MIS, Víctor |
| spellingShingle |
Sansores-España DDS, Luis Carrillo-Avila DDS, MINE, Arelly Sauri-Esquivel DDS, MO, Eduardo Guzmán-Marín MD, MSc, PhD, Eugenia Hernández DDS, MSc, PhD, Marcela Pozos-Guillén DDS, MSc, PhD, Amaury Martínez-Aguilar DDS, MIS, Víctor Quantification of Chemokine CCL5 in Patients with Diabetes Mellitus Type 2 and/or Chronic Periodontitis: Preliminary Study |
| author_facet |
Sansores-España DDS, Luis Carrillo-Avila DDS, MINE, Arelly Sauri-Esquivel DDS, MO, Eduardo Guzmán-Marín MD, MSc, PhD, Eugenia Hernández DDS, MSc, PhD, Marcela Pozos-Guillén DDS, MSc, PhD, Amaury Martínez-Aguilar DDS, MIS, Víctor |
| author_sort |
Sansores-España DDS, Luis |
| title |
Quantification of Chemokine CCL5 in Patients with Diabetes Mellitus Type 2 and/or Chronic Periodontitis: Preliminary Study |
| title_short |
Quantification of Chemokine CCL5 in Patients with Diabetes Mellitus Type 2 and/or Chronic Periodontitis: Preliminary Study |
| title_full |
Quantification of Chemokine CCL5 in Patients with Diabetes Mellitus Type 2 and/or Chronic Periodontitis: Preliminary Study |
| title_fullStr |
Quantification of Chemokine CCL5 in Patients with Diabetes Mellitus Type 2 and/or Chronic Periodontitis: Preliminary Study |
| title_full_unstemmed |
Quantification of Chemokine CCL5 in Patients with Diabetes Mellitus Type 2 and/or Chronic Periodontitis: Preliminary Study |
| title_sort |
quantification of chemokine ccl5 in patients with diabetes mellitus type 2 and/or chronic periodontitis: preliminary study |
| publisher |
Universidad de Costa Rica |
| publishDate |
2017 |
| url |
https://revistas.ucr.ac.cr/index.php/Odontos/article/view/28052 |
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