Mineral Trioxide Aggregate and Calcium Hydroxide Promotes In Vivo Intratubular Mineralization
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| Formato: | Online |
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Universidad de Costa Rica
2016
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| Acceso en línea: | https://revistas.ucr.ac.cr/index.php/Odontos/article/view/23548 |
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ODONTOS235482021-06-09T22:14:03Z Mineral Trioxide Aggregate and Calcium Hydroxide Promotes In Vivo Intratubular Mineralization Reyes-Carmona DDS, MSD, PhD, Jessie Santos PhD, Adair Cordeiro DDS, PhD, Mabel Apatite Bioactivity Biomineralization Calcium hydroxide (Ca(OH)²) Mineral Trioxide Aggregate (MTA). Literature showed that the interaction of Mineral Trioxide Aggregate (MTA) with dentin in phosphate-buffered saline (PBS) promotes a biomineralization process that leads to the formation of an interfacial layer with mineralized structures at the cement-dentin interface. Thus, we investigated the in vivo biomineralization process promoted by MTA and Ca(OH)² with dentin. Human dentin tubes filled with ProRoot MTA, Ca(OH)² or kept empty were implanted in subcutaneous tissues in the back of mice. After 12h, 1, 3, 7, 15, 30 and 60 days, the dentin tubes were processed for Scanning Electron Microscope (SEM) observations. SEM examination showed the presence of apatite-like clusters on collagen fibrils over the surface of tubes containing the biomaterials. This mineral deposition was more extensive and compact through time. At day 7, a compact layer of apatite was formed. The MTA/Ca(OH)² -dentin interface showed intratubular mineralization as early as 12h post-implantation. MTA and Ca(OH)² in an in vivo environment promoted a biomineralization process with dentin, simultaneously to the acute inflammatory response. MTA triggered an earlier and denser interfacial layer. Universidad de Costa Rica 2016-03-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Article Laboratory research application/pdf text/html https://revistas.ucr.ac.cr/index.php/Odontos/article/view/23548 10.15517/ijds.v18i1.23548 Odovtos - International Journal of Dental Sciences; Vol. 18 No. 1 (2016): Odovtos - International Journal of Dental Sciences V.18, 1(January-April) 2016; 49-59 Odovtos International Journal of Dental Sciences; Vol. 18 Núm. 1 (2016): Odovtos - International Journal of Dental Sciences V.18, 1(January-April) 2016; 49-59 2215-3411 1659-1046 10.15517/ijds.v18i1 eng https://revistas.ucr.ac.cr/index.php/Odontos/article/view/23548/23776 https://revistas.ucr.ac.cr/index.php/Odontos/article/view/23548/23995 Copyright (c) 2016 Odovtos - International Journal of Dental Sciences |
| institution |
Universidad de Costa Rica |
| collection |
Odovtos International Journal of Dental Sciences |
| language |
eng |
| format |
Online |
| author |
Reyes-Carmona DDS, MSD, PhD, Jessie Santos PhD, Adair Cordeiro DDS, PhD, Mabel |
| spellingShingle |
Reyes-Carmona DDS, MSD, PhD, Jessie Santos PhD, Adair Cordeiro DDS, PhD, Mabel Mineral Trioxide Aggregate and Calcium Hydroxide Promotes In Vivo Intratubular Mineralization |
| author_facet |
Reyes-Carmona DDS, MSD, PhD, Jessie Santos PhD, Adair Cordeiro DDS, PhD, Mabel |
| author_sort |
Reyes-Carmona DDS, MSD, PhD, Jessie |
| title |
Mineral Trioxide Aggregate and Calcium Hydroxide Promotes In Vivo Intratubular Mineralization |
| title_short |
Mineral Trioxide Aggregate and Calcium Hydroxide Promotes In Vivo Intratubular Mineralization |
| title_full |
Mineral Trioxide Aggregate and Calcium Hydroxide Promotes In Vivo Intratubular Mineralization |
| title_fullStr |
Mineral Trioxide Aggregate and Calcium Hydroxide Promotes In Vivo Intratubular Mineralization |
| title_full_unstemmed |
Mineral Trioxide Aggregate and Calcium Hydroxide Promotes In Vivo Intratubular Mineralization |
| title_sort |
mineral trioxide aggregate and calcium hydroxide promotes in vivo intratubular mineralization |
| publisher |
Universidad de Costa Rica |
| publishDate |
2016 |
| url |
https://revistas.ucr.ac.cr/index.php/Odontos/article/view/23548 |
| work_keys_str_mv |
AT reyescarmonaddsmsdphdjessie mineraltrioxideaggregateandcalciumhydroxidepromotesinvivointratubularmineralization AT santosphdadair mineraltrioxideaggregateandcalciumhydroxidepromotesinvivointratubularmineralization AT cordeiroddsphdmabel mineraltrioxideaggregateandcalciumhydroxidepromotesinvivointratubularmineralization |
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